Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 16, Issue 8, Pages 4203-4221Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2008.02.069
Keywords
tetramic acids; tetronic acids; bioactivity; biosynthesis; natural products
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Significant developments in the isolation of tetramic acids and tetronic acids, in the elucidation of their biosyntheses and their biological activities and in laboratory syntheses are reviewed with a focus on those derivatives with medicinal and pharmacological relevance. Important new members of the title compound families isolated since the year 2000 are covered as well as new biological aspects of some earlier congeners. (C) 2008 Elsevier Ltd. All rights reserved.
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