Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 16, Issue 8, Pages 4516-4522Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2008.02.055
Keywords
1-(3,5-Diaryl-4,5-dihydro-1H-pyrazol-4 yl)-1H-imidazole derivatives; antifungal and antimycobacterial activity
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1-(3,5- Diaryl-4,5-dihydro-1H-pyrazol-4-yl)-1H-imidazole derivatives were synthesized and tested for their in vitro antifungal and antimycobacterial activities. These imidazole derivatives showed an excellent antifungal activity against a clinical strain of Candida albicans and an interesting antitubercular activity against Mycobacterium tuberculosis H(37)Rv reference strain. (c) 2008 Elsevier Ltd. All rights reserved.
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