4.0 Article

Resonance assignments of human C35 (C17orf37) protein, a novel tumor biomarker

Journal

BIOMOLECULAR NMR ASSIGNMENTS
Volume 4, Issue 2, Pages 191-193

Publisher

SPRINGER
DOI: 10.1007/s12104-010-9218-9

Keywords

C35; C17orf37; Tumor biomarker; Resonance assignment

Funding

  1. National Research Program for Genomic Medicine
  2. National Science Council, Taiwan [NSC96-2113-M-002-028-MY2, NSC97-2113-M-002-005-MY2]

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A new tumor-specific target, termed C35 (C17orf37), has been identified by representational difference analysis of tumor and normal human mammary cell lines. C35 protein is considered to be an important target for cancer therapy, since the over expression of C35 functionally enhances migration and invasion of tumor cells. Here we report the NMR resonance assignments of C35 protein for further structural determination and functional studies.

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