4.7 Article

Antioxidative and free radical scavenging activities of selected medicinal herbs

Journal

LIFE SCIENCES
Volume 66, Issue 8, Pages 725-735

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0024-3205(99)00643-8

Keywords

medicinal herbs; antioxidant; free radical; peroxidation

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The antioxidative and superoxide- and hydroxyl radical-scavenging activities and prooxidant effect of twelve selected medicinal herbs were studied. The aqueous extracts of Coptis chinensis, Paeonia suffruticosa, Prunella vulgaris and Senecio scandens exhibited the highest potency in inhibiting rat erythrocyte hemolysis and lipid peroxidation in rat kidney and brain homogenates. The aforementioned four herbs also demonstrated strong superoxide- and hydroxyl radical-scavenging activity, but exerted only a slight pro-oxidant effect.

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