Journal
TETRAHEDRON LETTERS
Volume 41, Issue 5, Pages 703-706Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(99)02143-7
Keywords
isopentenyl diphosphate; 2-C-methyl-D-erythritol 4-phosphate; 4-(cytidine 5 '-diphospho)-2-C-methyl-D-erythritol; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
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2-C-Methyl- D-erythritol-4-phosphate is transformed to 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol in the presence of cytidine 5'-triphosphate by a novel Escherichia coli enzyme, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, involved in the nonmevalonate pathway. (C) 2000 Elsevier Science Ltd. All rights reserved.
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