Journal
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
Volume 58, Issue -, Pages -Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/bmt-2013-4129
Keywords
Magnetic drug targeting; nanoparticles; alternating current magnetic field; hyperthermia
Categories
Funding
- BMBF-Spitzencluster [01EX1012B]
- DFG [AL 552/3-3]
- Else Kroner-Fresenius-Stiftung, Bad Homburg vor der Hohe, Germany
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A new alternating current (AC) magnetic field applicator was designed to induce hyperthermia in an animal tumour model using superparamagnetic iron oxide nanoparticles (SPION). First experiments on phantoms including different concentrations of SPION were conducted. The results confirmed that the new AC magnetic field applicator could heat-up SPION. This proofs the capability to induce hyperthermia by SPION, dependent on the concentration.
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