Journal
ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE
Volume 30, Issue 1, Pages 45-51Publisher
KLUWER ACADEMIC PUBL
DOI: 10.1023/A:1006683507864
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Oligonucleotide 5'-polyphosphates are formed under potentially prebiotic conditions from oligonucleotide 5'-phosphates and sodium trimetaphosphate. Oligonucleotides activated as polyphosphates undergo template-directed ligation. We believe that these reactions could have produced longer oligonucleotide products from shorter substrates under prebiotic conditions.
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