4.2 Article

Automated Micro-PIV measurement in Lab-on-a-Chip systems

Journal

BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
Volume 57, Issue -, Pages 927-930

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/bmt-2012-4064

Keywords

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Funding

  1. European Union
  2. Free State of Saxony
  3. BMWI

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Flow rate and wall shear stress are important parameters for perfused cell culture systems and should be monitored. An easy and non-invasive method is the particle image velocimetry (PIV). In this work PIV was used to characterize a cell culture system with included peristaltic pump. The time-dependent flow profile was measured on several points of the chip for different pumping speeds to figure out which forces are applied to dissolved and adherent cells. The results can be used to improve the developed pump in respect to its layout, the excitation and the position within the chip.

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