Journal
PHYSIOLOGICAL MEASUREMENT
Volume 21, Issue 1, Pages 155-163Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0967-3334/21/1/319
Keywords
lung impedance; lung water; diuretic; electrical impedance tomography; heart failure
Categories
Ask authors/readers for more resources
Monitoring patients with left ventricular failure can be difficult. Electrical impedance tomography (EIT) produces cross-sectional images of changes in the impedance of the thorax. We measured changes in the electrical impedance of the lung in nine volunteers following a diuretic challenge. The hypothesis was that lung impedance would increase with diuretic induced fluid loss. Heart rate, blood pressure and urine output were also recorded. After diuretic the mean urine output was 1220 mi compared with 187 mi after placebo. Following diuretic administration, mean thoracic impedance increased by 13.6% (p < 0.01) and lung impedance increased by 7.8% (p < 0.05). Taken as a group there was a correlation between overall impedance change and total urine output. However, for each individual, the time course of change in impedance and urine output did not correlate significantly. Our findings show that EIT may offer a better guide to the response of the lung to diuretic treatment than simply measuring urine output. The urine output is neither specific nor sensitive in the assessment of lung water. Mean lung impedance, however, is largely determined by lung water The study showed that lung impedance can be recorded at supra-normal values. EIT may help in the management of patients with excess lung water.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available