4.5 Article

Nasal polyposis: Role of subclinical delayed food hypersensitivity

Journal

OTOLARYNGOLOGY-HEAD AND NECK SURGERY
Volume 122, Issue 2, Pages 298-301

Publisher

MOSBY-YEAR BOOK INC
DOI: 10.1016/S0194-5998(00)70259-2

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Nasal polyposis is a common problem in otolaryngology. The cause remains unclear, and treatment with medication and surgery is often unsatisfactory, We present our controlled study, which suggests a strong association between food allergy and nasal polyposis. The study was conducted in 2 parts, A postal survey of 900 patients with nasal polyps showed 53 respondents (5.9%) had a known food allergy, In the prospective study, 80 nasal polyp patients and 36 control subjects completed intradermal tests for food allergy. Sixty-five nasal polyp patients (81%) and 4 control subjects (11%) had positive intradermal food test results. This is highly significant, We believe that food allergy may play a significant role in the pathogenesis of nasal polyposis and should be further studied.

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