Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 12, Issue 1, Pages 57-62Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(99)00057-5
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- NIGMS NIH HHS [GM-52111] Funding Source: Medline
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Cytoskeleton-associated motor proteins typically drive organelle movements in eukaryotic cells in a manner that is tightly regulated, both spatially and temporally In the past year, a novel organelle transport mechanism utilizing actin polymerization was described. Important advances were also made in the assignment of functions to several new motors and in our understanding of how motor proteins are regulated during organelle transport. In addition, insights were gained into how and why organelles are transported cooperatively along the microtubule and actin cytoskeletons, and into the importance of motor-mediated transport in the organization of the cytoskeleton itself.
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