Journal
BIOSYSTEMS
Volume 55, Issue 1-3, Pages 129-136Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0303-2647(99)00090-8
Keywords
genetic regulatory networks; neural networks; gene expression
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We have modeled genetic regulatory net works in the framework of continuous-time recurrent neural networks. A method for determining the parameters of such networks, given expression level time series data, is introduced and evaluated using artificial data. The method is also applied to a set of actual expression data from the development of rat central nervous system. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
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