4.7 Article

Growth factor signaling to mTORC1 by amino acid-laden macropinosomes

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1

Wilhelm Palm et al.

Article Neurosciences

A Novel Size-Based Sorting Mechanism of Pinocytic Luminal Cargoes in Microglia

Cong Chen et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Manuele Rebsamen et al.

NATURE (2015)

Article Multidisciplinary Sciences

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

Shuyu Wang et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Differential regulation of mTORC1 by leucine and glutamine

Jenna L. Jewell et al.

SCIENCE (2015)

Letter Biochemical Research Methods

Improved vectors and genome-wide libraries for CRISPR screening

Neville E. Sanjana et al.

NATURE METHODS (2014)

Review Cell Biology

Regulation of mTORC1 by amino acids

Liron Bar-Peled et al.

TRENDS IN CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Inhibition of AMPK Catabolic Action by GSK3

Tsukasa Suzuki et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso et al.

NATURE (2013)

Review Cell Biology

Amino acid signalling upstream of mTOR

Jenna L. Jewell et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Rab5 Proteins Regulate Activation and Localization of Target of Rapamycin Complex 1

Dave Bridges et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Biochemistry & Molecular Biology

Amino acids and mTORC1: from lysosomes to disease

Alejo Efeyan et al.

TRENDS IN MOLECULAR MEDICINE (2012)

Article Biology

A growth factor signaling cascade confined to circular ruffles in macrophages

Timothy P. Welliver et al.

BIOLOGY OPEN (2012)

Article Biochemistry & Molecular Biology

A drug targeting only p110α can block phosphoinositide 3-kinase signalling and tumour growth in certain cell types

Stephen Jamieson et al.

BIOCHEMICAL JOURNAL (2011)

Review Biochemistry & Molecular Biology

Endosome maturation

Jatta Huotari et al.

EMBO JOURNAL (2011)

Article Biochemistry & Molecular Biology

Redox Regulates Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity by Modulating the TSC1/TSC2-Rheb GTPase Pathway

Sei Yoshida et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Cell Biology

Ruffles limit diffusion in the plasma membrane during macropinosome formation

Timothy P. Welliver et al.

JOURNAL OF CELL SCIENCE (2011)

Article Biochemistry & Molecular Biology

Rac1 Regulates the Activity of mTORC1 and mTORC2 and Controls Cellular Size

Abdelhafid Saci et al.

MOLECULAR CELL (2011)

Review Oncology

The biological and therapeutic relevance of mRNA translation in cancer

Sarah P. Blagden et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2011)

Review Cell Biology

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Cell Biology

Coordination of the Rab5 Cycle on Macropinosomes

William D. Feliciano et al.

TRAFFIC (2011)

Review Biochemistry & Molecular Biology

Virus Entry by Endocytosis

Jason Mercer et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)

Article Biochemistry & Molecular Biology

Regulation of mTORC1 by the Rab and Arf GTPases

Li Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

The Late Endosome is Essential for mTORC1 Signaling

Rory J. Flinn et al.

MOLECULAR BIOLOGY OF THE CELL (2010)

Article Cell Biology

A unique platform for H-Ras signaling involving clathrin-independent endocytosis

Natalie Porat-Shliom et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

Review Cell Biology

Shaping cups into phagosomes and macropinosomes

Joel A. Swanson

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Yasemin Sancak et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis

Ya-Sheng Gao et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Cell Biology

Differential association of phosphatidylinositol 3-kinase, SHIP-1, and PTEN with forming phagosomes

Lynn A. Kamen et al.

MOLECULAR BIOLOGY OF THE CELL (2007)

Review Multidisciplinary Sciences

Ras, PI(3)K and mTOR signalling controls tumour cell growth

Reuben J. Shaw et al.

NATURE (2006)

Article Multidisciplinary Sciences

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

PP Roux et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Cell Biology

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis

AD Hoppe et al.

MOLECULAR BIOLOGY OF THE CELL (2004)

Article Medicine, Research & Experimental

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

HB Zhang et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Multidisciplinary Sciences

Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor

AF Straight et al.

SCIENCE (2003)

Article Cell Biology

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

K Inoki et al.

NATURE CELL BIOLOGY (2002)