Journal
TETRAHEDRON LETTERS
Volume 41, Issue 6, Pages 859-862Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(99)02210-8
Keywords
alkaloids; biogenesis; biomimetic; indole; quinoline; terpene
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A biogenetically patterned synthetic route to the monoterpenoid quinoline alkaloids 20-deoxycamptothecin and (+/-)-camptothecin from secologanin and tryptamine via vincoside/strictosidine lactams has now been realized, and hence afforded likely biosynthetic intermediates for testing in vivo. (C) 2000 Elsevier Science Ltd. All rights reserved.
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