Journal
PHYSICAL REVIEW LETTERS
Volume 84, Issue 6, Pages 1343-1346Publisher
AMER PHYSICAL SOC
DOI: 10.1103/PhysRevLett.84.1343
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For plane-wave and many-spiral states of the experimentally bac;ed Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that a space-time-adaptive time-integration algorithm can achieve a factor of 5 reduction in computational effort and memory - but without a reduction in accuracy - when compared to an algorithm using a uniform space-time mesh at the finest resolution. Our results indicate that such an algorithm can be extended straightforwardly to simulate quantitatively three-dimensional electrical dynamics over the whole human heart.
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