4.8 Article

The total synthesis of pantocin B

Journal

ORGANIC LETTERS
Volume 2, Issue 3, Pages 319-321

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol991264x

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Funding

  1. NCI NIH HHS [CA24487] Funding Source: Medline
  2. NIGMS NIH HHS [GM08500] Funding Source: Medline

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[GRAPHICS] Pantocin B, an unusual antibiotic produced by Erwinia herbicola, effectively controls E. amylovora, the pathogen causing the plant disease fire blight. A total synthesis of pantocin B from L-alanine, glycine, and L-malic acid is reported.

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