Journal
TETRAHEDRON LETTERS
Volume 41, Issue 7, Pages 1051-1053Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(99)02231-5
Keywords
carbonylation; cyclisation; quinazolines; quinazolinones
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Chemical fixation of carbon dioxide was performed under mild conditions. Carbon dioxide (1 atm) easily reacted with 2-aminobenzonitriles at 20 degrees C, assisted by DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) to give 2,4-dihydroxyquinazolines in excellent yields. (C) 2000 Elsevier Science Ltd. All rights reserved.
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