4.8 Article

Mitochondrial FtsZ in a chromophyte alga

Journal

SCIENCE
Volume 287, Issue 5456, Pages 1276-1279

Publisher

AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.287.5456.1276

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A homolog of the bacterial cell division gene ftsZ was isolated from the alga Mallomonas splendens. The nuclear-encoded protein (MsFtsZ-mt) was closely related to FtsZs of the alpha-proteobacteria, possessed a mitochondrial targeting signal, and localized in a pattern consistent with a role in mitochondrial division. Although FtsZs are known to act in the division of chloroplasts, MsFtsZ-mt appears to be a mitochondrial FtsZ and may represent a mitochondrial division protein.

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