Journal
AMERICAN JOURNAL OF PSYCHIATRY
Volume 157, Issue 3, Pages 438-443Publisher
AMER PSYCHIATRIC PRESS, INC
DOI: 10.1176/appi.ajp.157.3.438
Keywords
-
Categories
Funding
- NIMH NIH HHS [MH-37592, MH-01206, MH-50727] Funding Source: Medline
Ask authors/readers for more resources
Objective: The authors' goal was to investigate the suggestion of previous investigations that prenatal viral exposures might increase the later risk of psychotic disorders. Method: They conducted a follow-up study in young adulthood of a birth cohort that was previously documented, by clinical examination and serological testing, to have in utero rubella exposure during the 1964 rubella epidemic. Data were also obtained from an unexposed birth cohort and from the Epidemiological Catchment Area survey. Young adult subjects were administered a standard psychiatric diagnostic interview. The authors compared the proportions of subjects with nonaffective psychosis in the exposed and unexposed cohorts. Results: The rubella-exposed subjects, most of whom were exposed in the first trimester, demonstrated a substantially greater risk for nonaffective psychosis than the subjects who were not exposed to rubella (relative risk = 5.2). Conclusions: There is an association between clinically and serologically diagnosed prenatal viral infection and nonaffective psychosis in adulthood.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available