Journal
BRAIN RESEARCH
Volume 858, Issue 2, Pages 440-445Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0006-8993(00)02029-1
Keywords
conditioned fear; blood pressure; heart rate; radio-telemetry; freezing; exploratory behavior
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This study compares the time course of the cardiovascular changes (mean arterial blood pressure, heart rate) and behavioral changes (freezing, rearing, grooming and activity) evoked by 30 min long exposures to a footshock chamber before and after conditioning with footshocks. The main finding is that the conditioned fear evoked by re-exposure to the footshock chamber after conditioning is associated with a prolonged freezing response, a marked rise in mean arterial pressure (+ 35 mm Hg above a resting baseline of 105 mm Hg) and a delayed rise in heart rate. The pattern of behavioral and cardiovascular changes is the same as with conditioned fear to a discrete stimulus but the effect is a lot longer. (C) 2000 Elsevier Science B.V. All rights reserved.
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