4.8 Article

Three-channel fluorescent sensing via organic white light-emitting dyes for detection of hydrogen sulfide in living cells

Journal

BIOMATERIALS
Volume 34, Issue 30, Pages 7429-7436

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.biomaterials.2013.06.013

Keywords

Fluorescent sensors; ESIPT; Three-channel; Hydrogen sulphide; Cellular imaging

Funding

  1. NSFC [20872032, 20972044, 21172063]
  2. NCET [08-0175]
  3. HNNSF [13JJ3117]
  4. Doctoral Fund of Chinese Ministry of Education [20100161110008]

Ask authors/readers for more resources

To demonstrate the feasibility of development of three-channel based fluorescent sensors based on organic white light-emitting dyes, in this work, for proof-of-principle, we initially judiciously designed an organic white light-emitting dye, which was further used as a robust platform to engineer a new fluorescent sensor for monitoring H2S with turn-on fluorescence signals in blue, green, and red emission channels in both solution and living cells. This work should open a new avenue for design of three- and multiple-channel based fluorescent sensors for various analytes. (C) 2013 Elsevier Ltd. All rights reserved.

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