Journal
BRAIN RESEARCH
Volume 860, Issue 1-2, Pages 181-189Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0006-8993(00)02013-8
Keywords
monoamines; amygdala; locus ceruleus; microdialysis; sleep; cat
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This is the first microdialysis report comparing concentrations (pg/mu l) of norepinephrine (NE), serotonin (5-HT) and dopamine (DA) derived from feline locus ceruleus complex (LC) and amygdala. NE and 5-HT declined progressively from waking to slow-wave-sleep (SWS) and then to rapid-eye-movement (REM) sleep. Concentrations of DA did not change at either collection site across the sleep-wake cycle. We conclude that release of NE and 5-HT release modulates physiologic components related to the sleep-wake cycle, but DA does not. (C) 2000 Elsevier Science B.V. All rights reserved.
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