Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 12, Issue 2, Pages 204-210Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0955-0674(99)00077-0
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Endocytosis of ligand-activated receptors has generally been considered a mechanism to attenuate signaling. There is now a growing body of evidence suggesting that this process is much more sophisticated and that endocytic membrane trafficking regulates both the intensity of signaling and the co-localization of activated receptors with downstream signaling molecules.
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