Journal
CURRENT OPINION IN MICROBIOLOGY
Volume 3, Issue 2, Pages 165-170Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S1369-5274(00)00070-9
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Funding
- NIGMS NIH HHS [GM19416] Funding Source: Medline
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Two-component and phosphorelay signal transduction systems are the major means by which bacteria recognize and respond to a variety of environmental stimuli. Recent results have implicated these systems in the regulation of a variety of essential processes including cell-cycle progression, pathogenicity, and developmental pathways. Elucidation of the structures of the interacting domains is leading to an understanding of the mechanisms of molecular recognition and phosphotransfer in these systems.
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