Journal
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS & EXPRESS LETTERS
Volume 39, Issue 4A, Pages L269-L270Publisher
JAPAN SOC APPLIED PHYSICS
DOI: 10.1143/JJAP.39.L269
Keywords
deoxyribonucleic acid (DNA); poly(dA-dT) poly(dA-dT); mica; surface atomic force microscopy (AFM); DNA network; DNA film
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We have successfully fabricated large-scale deoxyribonucleic acid (DNA) networks on mica surfaces using a simple and easy fabrication method for the first time. Sample drops of poly(dA-dT). poly(dA-dT) which is a synthetic linear DNA were spotted on freshly cleaved mica and blown off with air. At low DNA concentrations, clusters of DNA molecules were separated from each other. However at high concentrations, substrates were covered with a two-dimensional DNA network measuring more than 12 mm laterally. The DNA network discovered in our study seems highly practical due to its simple and easy fabrication method and its length. We believe this DNA network has the potential to serve as a biomaterial for medical, engineering and environmental applications.
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