Journal
BIOLOGICAL PSYCHIATRY
Volume 47, Issue 7, Pages 626-633Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0006-3223(99)00161-4
Keywords
depression; sleep; first-night effect; polysomnography; spectral analysis; slow-wave sleep
Categories
Ask authors/readers for more resources
Background: The aim of the present study was to evaluate the first-night effect in depressed inpatients, using standard sleep measures as well as all-night spectral analysis of the sleep electroencephalogram (EEG). Methods: Eighteen drug-ft-ee, depressed inpatients were studied for 3 consecutive nights in the hospital sleep laboratory. Results: Visual sleep scoring results showed a slight brit measurable first-night effect, characterized by a reduction of rapid eve movement (REM) sleep amount and increased wakefulness. Sleep EEG spectral analysis showed significantly reduced delta (p < .01) and theta (p < .05) power density in non-REM (NREM) sleep of the first night compared with that of the second and third nights. These differences were limited To the early part of the sleep period a time during the night that is particularly vulnerability to the effects of depressive disorder. In contrast to the NREM sleep findings, spectral REM variables studied did not significantly vary across the three nights. Conclusions: The results obtained suggest that first-night data should not be simply discarded brit could be used in subsequent analyses and could be considered useful in the evaluation of the sleep of depressed patients. (C) 2000 Society of Biological Psychiatry.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available