Journal
JOURNAL OF VIROLOGY
Volume 74, Issue 8, Pages 3905-3908Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.74.8.3905-3908.2000
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Funding
- NINDS NIH HHS [R01 NS018596, R01-NS18596] Funding Source: Medline
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Antibodies clear Sindbis virus from infected animals through an unknown mechanism. To determine whether interferon-induced pathways are required for this clearance, we examined mice which are unable to respond to alpha/beta interferon or gamma interferon, Although extremely susceptible to infection, such mice survived and completely cleared virus if antibodies against Sindbis virus were given.
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