Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 107, Issue 2, Pages 191-205Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0166-6851(00)00185-7
Keywords
Plasmodium falciparum; mitochondria; succinate dehydrogenase; SDHA; SDHB
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DNA, as well as almost all the conserved amino acids indispensable for substrate binding and the catalytic reaction were found in these peptides, indicating the functional importance of this enzyme in the parasite. Interestingly, a P. falciparum-specific insertion and a unicellular organism-specific deletion were found in the amino acid sequence of Fp. This is the first report of the primary structure of the protozoan succinate dehydrogenase. (C) 2000 Elsevier Science B.V. All rights reserved.
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