Journal
BIOMARKERS
Volume 19, Issue 6, Pages 444-451Publisher
INFORMA HEALTHCARE
DOI: 10.3109/1354750X.2014.926567
Keywords
Gastric carcinoma; neutrophil-lymphocyte ratio; platelet-lymphocyte ratio; prognosis
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Funding
- National Basic Research Program of China (973 Program) [2010CB529301]
- Key Program for Anti-cancer Research of Tianjin Municipal Science and Technology Commission [12ZCDZSY16400]
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The objective of this study was to investigate the impact of neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) on the postoperative complication and long-term outcomes in patients with resectable gastric cancer (GC). A total of 377 patients who underwent curative resection for GC were enrolled. In logistic analysis, PLR (p=0.09) was independently associated with the incidence of postoperative complication. The results of multivariate survival analysis showed the NLR and PLR were introduced as prognostic factors for operable GC, the NLR may represent a useful prognostic index for the prediction of overall survival (OS) in advanced GC (p=0.021).
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