Journal
TETRAHEDRON LETTERS
Volume 41, Issue 17, Pages 3029-3033Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)00341-5
Keywords
benzothiazepine; combinatorial chemistry; solid-phase synthesis
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A new solid-phase efficient route to 1,5-benzothiazepine-4-one derivatives is reported. The synthesis exploits the variety of halo-nitrobenzene derivatives available and the facile substitution of the benzamide nitrogen. A wide range of derivatives can be obtained in excellent purity. (C) 2000 Elsevier Science Ltd. All rights reserved.
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