Journal
BIOMARKERS
Volume 16, Issue 2, Pages 106-111Publisher
INFORMA HEALTHCARE
DOI: 10.3109/1354750X.2010.533286
Keywords
Biomarkers; periodontitis; inflammation; atherosclerosis; diabetes
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Funding
- Japanese Society for the Promotion of Science [19592398, 19592420, 21792164]
- Ministry of Education, Culture, Science, Sports and Technology (MEXT)
- Osaka Dental University [07-05]
- Grants-in-Aid for Scientific Research [19592398, 22592323, 19592420, 22592105, 21792164, 23593113] Funding Source: KAKEN
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Methods: A cross-sectional study was conducted using oral and systemic health checkup data of 151 middle-aged men. The serum levels of adiponectin and its subfractions were also analysed. Results: The ratio of high molecular weight adiponectin to total adiponectin was significantly lower in subjects with periodontal pockets. Moreover, this ratio independently associated with periodontal condition. Conclusions: The ratio of HMW adiponectin to total adiponectin could be a novel biomarker for evaluation of periodontal health in middle-aged men.
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