Journal
TETRAHEDRON LETTERS
Volume 41, Issue 18, Pages 3415-3418Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(00)00396-8
Keywords
Amberlyst-15; S(N)2 ' oxaspirocyclization; secondary allylic alcohols; total synthesis; theaspirane; theaspirone
Categories
Ask authors/readers for more resources
A variety of substituted 1-oxaspiro[4.4]non-6-ene, 1-oxaspiro[4.5]dec-6-ene, 6-oxaspiro[4.5]dec-l-ene and 1-oxaspiro[5.5]undec-7-ene systems have been prepared by utilizing Amberlyst-15-catalyzed intramolecular S(N)2' oxaspirocyclizations of secondary allylic alcohols under mild reaction conditions in quantitative yields. This oxaspirocyclization was applied to the total synthesis of theaspirane and theaspirone from beta-ionone in five steps. (C) 2000 Elsevier Science Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available