Journal
BIOMACROMOLECULES
Volume 15, Issue 6, Pages 2012-2018Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm500159r
Keywords
-
Funding
- Grants-in-Aid for Scientific Research [26702017, 26106709] Funding Source: KAKEN
Ask authors/readers for more resources
In this study, we fabricated lectin-tagged fluorescent polymeric nanoparticles approximately 35 nm in diameter using biocompatible polymers conjugated with lectins for the purpose of detecting sialic acid on a living cell surface, which is one of the most important biomarkers for cancer diagnosis. Through cellular experiments, we successfully detected sialic acid overexpression on cancerous cells with high specificity. These fluorescent polymeric nanoparticles can be useful as a potential bioimaging probe for detecting diseased cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available