Journal
BIOMACROMOLECULES
Volume 14, Issue 1, Pages 186-192Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm3015736
Keywords
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Funding
- Research Councils U.K. (RCUK)
- EPSRC [EP/I014454/1]
- BBSRC [BB/I002847/1]
- Royal Society [RG100120]
- Biotechnology and Biological Sciences Research Council [BB/I002847/1] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/I014454/1] Funding Source: researchfish
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A novel method for the production of inhibitor-and solvent-free resins suitable for three-dimensional (3D) microstereolithography is reported. Using an exemplar poly(ethylene glycol) based resin, the control of features in the X, Y, and Z planes is demonstrated such that complex structures can be manufactured Human mesenchymal stem cells cultured on the manufactured scaffolds remained viable during the 7 day assessment period, with proliferation rates comparable to those observed on tissue culture polystyrene. These data suggest that this novel, yet simple, method is suitable for production of 3D scaffolds for tissue engineering and regenerative medicine applications.
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