Journal
BIOMACROMOLECULES
Volume 12, Issue 12, Pages 4173-4177Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm2009922
Keywords
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Funding
- TOYOTA motor corporation
- Japan Society for the Promotion of Science [20681013, 23570181]
- Grants-in-Aid for Scientific Research [20681013, 22655059, 22350076, 23570181] Funding Source: KAKEN
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A chemically cross-linked filamentous actin (F-actin) gel consisting of globular actin (G-actin) as repeating units was prepared. The F-actin gel was cross-linked by covalent bonds, and the main chain is represented by the self assembly of G-actin with a high-ordered hierarchical structure. The gel. exhibited good mechanical performance with a storage modulus >1 kPa and undergoes reversible sol-gel transitions. in response to changes in the salt concentration (chemical induced sol-gel transition) as well as to shear strain (mechanical-induced sol-gel transition). Therefore, the gel exhibits self repairing ability through dynamic polymerization and depolymerization across the structure hierarchies under repeated shear stress.
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