Journal
BIOMACROMOLECULES
Volume 12, Issue 12, Pages 4178-4182Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm201214r
Keywords
-
Funding
- National Science Foundation [CBET-0730292, DGE-0221651]
- National Institutes of Health [5-P20-RR016472-10]
- Procter and Gamble Company
Ask authors/readers for more resources
A combination of sample manipulation and rheological characterization at the microscale is used to identify the gelation of poly(ethylene glycol)-heparin hydrogels over a wide range of compositions. A microfluidic device produces 50-100 droplet samples, each with a different composition. Multiple particle tracking microrheology is used to measure the rheological state of each sample. This combination requires little material and enables efficient and rapid screening of gelation conditions. The high resolution data identifies the gelation reaction percolation boundaries and a lower limit of the total hydrogelator concentration for gelation to occur, which can be used for the subsequent engineering, testing, and processing of these materials.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available