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Mitochondrial control of cell death

Journal

NATURE MEDICINE
Volume 6, Issue 5, Pages 513-519

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/74994

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In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.

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