Journal
BIOMACROMOLECULES
Volume 10, Issue 9, Pages 2565-2570Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bm900519v
Keywords
-
Funding
- NSF [CMMI 0600583, CBET 0731096]
Ask authors/readers for more resources
The microstructure of type I collagen, consisting of alternating gal) and overlap regions with a characteristic D period of similar to 67 nm, enables multifunctionalities of collagen fibrils in different tissues. Implementing near-surface dynamic and static nanoindentation techniques with atomic force microscope, we reveal mechanical heterogeneity,to along the axial direction of a single isolated collagen fibril from tendon and show that, within the D period, the gap and overlap regions have significantly different elastic and energy dissipation properties, correlating the significantly different molecular structures in these two regions. We further show that such subfibrillar heterogeneity holds in collagen fibrils inside bone and might be intrinsically related to the excellent energy dissipation performance of bone.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available