4.7 Article

Synthesis and Antimicrobial Properties of Novel Silver/Polyrhodanine Nanofibers

Journal

BIOMACROMOLECULES
Volume 9, Issue 10, Pages 2677-2681

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/bm800574x

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Funding

  1. Ministry of Commerce, Industry and Energy, Republic of Korea [SystemIC2010]
  2. Korea Evaluation Institute of Industrial Technology (KEIT) [10030559] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  3. National Research Foundation of Korea [과C6A1903] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Silver nanoparticle-embedded polyrhodanine nanofibers were synthesized by chemical oxidation polymerization. Silver ions were reduced to silver nanoparticles by oxidizing rhodanine monomer and simultaneously complexed with the rhodanine due to coordinative interactions, resulting in the formation of silver nanoparticle-embedded polyrhodanine nanofibers. The synthesized silver/polyrhodanine nanofiber was found to have the excellent antimicrobial activity against Gram-negative Escherichia coli, Gram-positive Staphylococcus aureus, and Candida albicans. The modified Kirby-Bauer test demonstrated that the silver/polyrhodanine nanofiber had better antimicrobial efficacy than silver sulfadiazine.

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