4.1 Review

Small regulatory non-coding RNAs in bacteria: physiology and mechanistic aspects

Journal

BIOLOGY OF THE CELL
Volume 101, Issue 2, Pages 117-131

Publisher

WILEY
DOI: 10.1042/BC20070137

Keywords

regulation; RNA duplex; RNA/protein interaction; RNA/RNA interaction; small non-coding RNAs

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Funding

  1. INSERM (Institut National de la Sante et de la Recherche Medicale)
  2. INRA (Institut National de la Recherche Agronomique)

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Regulatory ncRNAs (non-coding RNAs) adjust bacterial physiology in response to environmental cues. ncRNAs can base-pair to mRNAs and change their translation efficiency and/or their stability, or they can bind to proteins and modulate their activity. ncRNAs have been discovered in several species throughout the bacterial kingdom. This review illustrates the diversity of physiological processes and molecular mechanisms where ncRNAs are key regulators.

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