4.6 Article

Identification of monozygotic twins that are concordant for preeclampsia

Journal

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Volume 182, Issue 5, Pages 1156-1157

Publisher

MOSBY-YEAR BOOK INC
DOI: 10.1067/mob.2000.105429

Keywords

monozygotic twins; preeclampsia

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Preeclampsia is thought to be discordant in monozygotic twins. While recruiting for a genetic study into preeclampsia, we identified 4 sets of twins and a triplet gestation; all were monozygous on deoxyribonucleic acid fingerprinting. Two twins were concordant for preeclampsia, and 2 of the triplets had pregnancy-induced hypertension, although only 1 of them had proteinuria. Hence we confirm the existence of monozygotic twins that are concordant for preeclampsia.

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