Journal
DEVELOPMENT GENES AND EVOLUTION
Volume 210, Issue 5, Pages 270-275Publisher
SPRINGER VERLAG
DOI: 10.1007/s004270050314
Keywords
Dlx; homeobox; dentition; tooth
Funding
- NIDCR NIH HHS [DE 10871] Funding Source: Medline
Ask authors/readers for more resources
The mammalian Dir homeobox gene family has been shown to play multiple roles in tooth development, but a detailed comparison of the expression pattern of all members throughout tooth development has been lacking. We provide such an analysis for the six known murine Dir genes. The expression patterns for these genes allow a refinement of previously proposed models for the role of Dir genes in tooth type specification and raise the possibility of roles for subsets of these genes in tooth initiation, morphogenesis (enamel navel formation, enamel knot induction, cervical loop growth), and enamel formation. The relationship of Dir gene expression to their genomic organization suggests coordinate regulation of linked genes at early stages but regulatory differences at later stages.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available