4.4 Article

Functional neuroimaging of the olfactory system in humans

Journal

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
Volume 36, Issue 2, Pages 165-181

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/S0167-8760(99)00110-5

Keywords

amygdala; entorhinal cortex; functional MRI; gyrus rectus; olfaction; orbitofrontal; positron emission tomography; pyriform cortex

Funding

  1. NIMH NIH HHS [1F32MH11641-01A1] Funding Source: Medline

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Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) have begun to provide unique information regarding the neural underpinnings of olfactory functioning in humans. We review the relative strengths and weaknesses of PET and fMRI techniques for studying olfaction. We then review PET and fMRI studies relating to the olfactory functions of the pyriform cortex, orbitofrontal cortex, amygdala and the entorhinal/hippocampal region. A pixelwise correlational analysis of PET data is also presented in order to clarify the relationship between blood flow in the medial temporal lobes and psychoperceptual variables. (C) 2000 Elsevier Science B.V. All rights reserved.

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