4.4 Article

Hereditary pancreatic adenocarcinoma - A clinical perspective

Journal

MEDICAL CLINICS OF NORTH AMERICA
Volume 84, Issue 3, Pages 665-+

Publisher

W B SAUNDERS CO
DOI: 10.1016/S0025-7125(05)70249-2

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Funding

  1. NCI NIH HHS [5 P50 CA 72712, 5 P50 CA 62924] Funding Source: Medline

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Current estimates show that 5% to 10% of the pancreatic cancer burden is because of a primary genetic cause. This article presents an historical overview of hereditary pancreatic cancer. Genetic epidemiology studies and genetic disorders known to predispose to pancreatic cancer are reviewed, and important clinical issues pertaining to the management of these pancreatic cancer families are addressed.

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