Journal
MOLECULAR BRAIN RESEARCH
Volume 77, Issue 2, Pages 290-293Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0169-328X(00)00069-3
Keywords
interleukin 18; AcPL; binding protein; hypothalamus; RT-PCR
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Interleukin 18, an inflammatory cytokine, mediates its effects by interaction with its receptor complex, consisting of the IL-18 receptor (IL-18R) and receptor accessory protein (AcPL). A functional inhibitor of IL-18, the IL-18 binding protein (IL-18BF), has been identified recently. This study reports the detection of IL-18, IL-18R, AcPL and IL-18BP mRNA expression in the brain of normal adult rats using RT-PCR. (C) 2000 Elsevier Science B.V. All rights reserved.
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