Journal
TETRAHEDRON
Volume 56, Issue 20, Pages 3161-3165Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(00)00190-3
Keywords
thiazoles; amines; amino acids and derivatives; thiocyanates
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N-Substituted 2-aminothiazoles are synthesized in a one-pot procedure using readily available alpha-bromo ketones and amines. This method is compatible with a wide range of functional groups and offers a facile and efficient access to the class of N-thiazolyl alpha-amino acid derivatives. (C) 2000 Elsevier Science Ltd. All rights reserved.
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