Journal
NEUROREPORT
Volume 11, Issue 7, Pages 1523-1527Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200005150-00031
Keywords
decision-making; prefrontal cortex; thalamus
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Funding
- Wellcome Trust [090961] Funding Source: Medline
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This study demonstrates the neural system potentially involved in the representation of, and choice between, stimulus classifications in an ambiguous. novel, decision-making task. This difficult choice behaviour is taken as an example of a basic executive processing task. Subjects heard sounds that were consonant-vowel combinations that had been distorted and were required to categorize each stimulus as speech-like or not-speech-like. Cerebral activity was measured with positron emission tomography. A neural system (thalamic and medial prefrontal cortical regions) was demonstrated; there was greater activity involved in assigning the sound to the larger class of not-speech-like sounds than to the more restricted category of speech-like sounds. We interpret this activity as reflecting process and representation in a simple central executive task. NeuroReport 11:1523-1527 (C) 2000 Lippincott Williams & Wilkins.
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