Journal
ORGANIC LETTERS
Volume 2, Issue 10, Pages 1403-1406Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol005728z
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- NCI NIH HHS [T32CA09112] Funding Source: Medline
- NIGMS NIH HHS [GM58160] Funding Source: Medline
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The N-arylation of indoles, including a variety of substituted ones, has been carried out using bulky, electron rich phosphines as the supporting ligand in combination with Pd-2(dba)(3). Using this catalyst system, the efficient coupling of indole and a variety of substituted indoles with aryl iodides, bromides, chlorides, and triflates can be achieved.
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