Journal
CANCER LETTERS
Volume 153, Issue 1-2, Pages 189-197Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0304-3835(00)00374-8
Keywords
esophageal squamous cell carcinoma; lymph node micrometastasis; cytokeratin; postoperative recurrence; immunohistochemistry
Categories
Ask authors/readers for more resources
The lymph nodes of 59 patients with pNO esophageal squamous cell carcinomas were examined immunohistochemically using cytokeratin (CK) antibody. Primary tumors were immunostained with cyclin D1 (CD1) and E-cadherin (E-cad) antibody. Lymph node micrometastasis (MM) was found in 39 (55.5%) patients. Tumor recurrence was found in 17 patients and all but one of them had MM. The 5-year survival rate was significantly poorer in patients with MM than in those without MM. Almost all patients with positive CD1 and negative E-cad expression had MM. The examination of CD1 and E-cad expression in primary tumors may be useful for predicting MM. (C) 2000 Published by Elsevier Science Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available