Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 4, Issue 3, Pages 270-279Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(00)00088-0
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The principles of Darwinian evolution have been explored in molecular systems such as autocatalytic networks and dynamic combinatorial libraries. Molecular evolution in such systems manifests itself as ligand or receptor amplification by selection. Research efforts exploring these concepts may provide a mechanism far the identification of novel catalysts, molecular receptors and bioactive molecules.
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